Small studies have suggested that a common prostate cancer treatment might protect COVID-19 patients from becoming seriously ill. A new, larger study found no benefit, according to a report published on Friday in JAMA Network.
The treatment blocks the effects of androgen, a male hormone involved in fueling prostate cancer that also regulates a protein that plays a role in COVID-19 infections. Researchers studied 1,106 COVID-19 patients with prostate cancer, 24% of whom had received androgen deprivation therapy (ADT).
Thirty days after COVID-19 diagnosis, there was no difference in COVID-19 severity or death rates between men who did or did undergo ADT. The result was the same when researchers restricted the analysis to 477 men who were closely matched on the basis of similar health status and risk factors.
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“These findings do not support the hypothesis that ADT may be useful” for patients with COVID-19, the researchers concluded. But this observational study, they point out, cannot definitively prove whether or not ADT reduces COVID-19 severity. The answer to that question will come from large randomized trials that are currently underway.
Long COVID rare in college athletes
College athletes who become infected with the coronavirus are very unlikely to have any lasting effects, a large U.S. study suggests.
Researchers tracked more than 3,500 athletes from 44 colleges and universities and from more than 20 different sports who tested positive for the virus. Only 1.2% reported symptoms lasting more than three weeks, with 0.06% reporting symptoms lasting more than three months, the researchers wrote in the British Journal of Sports Medicine.
Four percent reported still having problems like shortness of breath or chest pain when they got back to exercising. Researchers found that one in four athletes with chest pain upon exercising had likely suffered some heart effects from the virus, whereas no athlete with exertional symptoms without chest pain appeared to have COVID-19 related heart issues.
“For the vast majority of athletes, this study shows that a return to play is possible without lingering COVID symptoms,” study leader Dr. Jonathan Drezner of the University of Washington in Seattle said in a statement.
“But any new chest pain or cardiopulmonary symptom should be taken seriously. Even if initial cardiac testing is negative after a COVID-19 illness, chest pain while exerting yourself should be evaluated.”
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